{"id":23884,"date":"2016-09-14T16:09:50","date_gmt":"2016-09-14T10:09:50","guid":{"rendered":"http:\/\/ipbb.kz\/eng\/?page_id=23884"},"modified":"2026-03-12T13:06:31","modified_gmt":"2026-03-12T07:06:31","slug":"laboratory-of-cell-engineering","status":"publish","type":"page","link":"https:\/\/ipbb.kz\/eng\/laboratory-of-cell-engineering\/","title":{"rendered":"Laboratory of Cell Engineering"},"content":{"rendered":"

\"%d1%83%d1%82%d0%b5%d1%83%d0%bb%d0%b8%d0%bd-%d0%ba%d0%b0%d0%b9%d1%80%d0%b0%d1%82-%d1%80%d0%b8%d0%b7%d0%b0%d0%b1%d0%b5%d0%ba%d0%be%d0%b2%d0%b8%d1%87\"<\/p>\n

Head of the laboratory<\/strong><\/p>\n

Dr. Kairat Uteulin,\u00a0 Professor<\/p>\n

Fax:\u00a0 +7(727) 394 7562<\/p>\n

Phone: 8 705 185 0224<\/p>\n

E-mail: gen_uteulink@mail.ru<\/p>\n

Author ID\u00a0Scopus\u00a0 6602865844<\/span><\/a><\/p>\n

Researcher ID Web of Science<\/span><\/a>\u00a0L-3508-2018<\/span><\/p>\n

ORCID ID 0000-0002-5459-0902<\/span><\/a><\/p>\n

 <\/p>\n

Laboratory staff<\/strong><\/p>\n

Kershanskaya O.I. — Chief Researcher, Doctor of Biological Sciences, Professor.<\/p>\n

Terletskaya N.V. — Leading Researcher, Candidate of Biological Sciences, Associate Professor.<\/p>\n

Lee T.E. — Leading Researcher, Candidate of Biological Sciences.<\/p>\n

Yesenbayeva G.L. — Senior Researcher, Candidate of Agricultural Sciences.<\/p>\n

Mukiyanova G.S. — Researcher, Ph. D.<\/p>\n

Bari G.T., — Researcher, Ph. D Student.<\/p>\n

Jobulaeva A.K. — Researcher, Master.<\/p>\n

Altaeva N.A. — Researcher.<\/p>\n

Kuly Zh. — Laboratory assistant, Master.<\/p>\n

Maulenbay A. — Laboratory assistant, Master.<\/p>\n

Sadullaeva Z.N. \u2013 Laboratory assistant.<\/p>\n

 <\/p>\n

The purpose of the laboratory strategy — development and introduction of physiological, biochemical and bioengineering methods of rapid creation, evaluation and breeding resistant to stress and crop yields.<\/p>\n

 <\/p>\n

The main directions of scientific research at laboratory:<\/strong><\/p>\n

Evaluation and establishment of the modern breakthrough biotechnologies for genetic engineering, metabolic engineering, …omix technologies, genes and genomes plant editing to create highly productive, disease and pest-resistant elite genotypes and cultivars of the major priority crops in agriculture.<\/strong><\/p>\n

Study of the biochemical and molecular genetic mechanisms of the resistance of grain and leguminous crops to abiotic stresses, and improving the quality and productivity.<\/p>\n

Development of technologies for introducing kok-saghyz, a domestic producer of natural rubber, into the culture.<\/p>\n

<\/u>\u00a0Main results of activity (for the last 5 years):<\/strong><\/p>\n

Genetic constructions of key genes to combat micropathogens and viruses penetration and infecting in barley have been created: Ac<\/em> gene — chitinase that destroys the cell wall of microfungies; constriction for plant CRISPR \/ Cas9 genome editing and knockout of gene eukaryotic virus translation initiation factor (eIF4E) that involved in translation of many viruses caused crops diseases. A new simple and effective genotype-independent germ-line biotechnology method for genetic transformation of barley has been developed and patented. Genetic editing approaches for the barley eIF4E gene have been developed, including bombardment and Agrobacterium tumefaciens<\/em> transformations. Genetic editing (modification) of the eIF4E gene is performing. Edited CRISPR \/ Cas9 barley lines with modification of the eIF4E gene resistant to many viral diseases will be created.<\/p>\n

Approaches to improve the natural resistance of plants to biotic stresses and to create disease-resistant soybean lines by genetic engineering of the phenylpropanoid cycle have been developed. Genetic engineering techniques for increasing the biosynthesis of lignin — a natural anti-microbial compound, to improve the control of micro-pathogens that caused diseases have been established. Genetic constructions of the key genes of phenylpropanoid cycle have been elaborated and applied in the genetic transformation of soybean: transcription factor Cs\/MYB4sens;<\/sub> the main lignification genes — 35S\/PAL5, C4H\/F5H, 35S\/CAD1, as well as gene antioxidant stress — FeSOD. The biotechnology of A. tumefaciens<\/em> mediated germ-line genetic transformation of soybean plants was elaborated and\u00a0 optimized for the introduction of key genes of lignin biosynthesis and resistance to biotic stresses and was used to obtain T0<\/sub> transgenes with the fficiency of beans forming 90% of transformed seeds number. Metabolic profiling of transgenic soybean plants showed a composition changing and an increasing of content of the most important metabolites of the phenylpropanoid cycle: flavonols, phenolic acids, genistin, saponins — antioxidants involved in protecting plants from biotic stresses.<\/p>\n

So, the transition from Genomics to Metabolomics was carried out by improving the most important metabolic process — the phenylpropanoid cycle in soybean plants using genetic engineering techniques to improve resistance to biotic stresses — diseases caused by micropathogens.<\/p>\n

New interspecific drought-resistant wheat hybrids with high grain quality for various purposes of the food industry were obtained.<\/p>\n

Kok-saghyz breeding technologies have been developed.<\/p>\n

Methods for the extraction of rubber from Kok-saghyz roots have been developed.<\/p>\n

\u00a0<\/em><\/p>\n

Projects and programs (for the last 5 years):<\/strong><\/p>\n

Project leader O. Kershanskaya 2018-2020. Program 217 «Development of Science.» 102 «Grant financing». Priority: Life Sciences. Project IRN AP05132774 «Evaluation and establishment of new biotechnologies for CRISPR\/Cas9 genes editing and germ-line genetic transformation to create elite disease-resistant barley cultivars in Kazakhstan».<\/p>\n

Project leader O. Kershanskaya 2013-2015. Sub-program 101 Grant funding research. Priority:\u00a0 Intellectual potential of the country. 0553 \/ GF3. «Improving the soybean’s resistance to biotic stresses through genetic engineering of the phenylpropanoid cycle».<\/p>\n

Project leader Terletskay N.V. 2018-2020 AP5131734 \u00abPhysiological and molecular genetic features of the functioning of the photosynthetic apparatus of alloplasmic lines of wheat, obtained as a result of interspecific crossings, in conection with their drought resistance\u00bb.<\/p>\n

Project leader Lee T.E. Identification high-protein soybean lines at the final stages of the breeding\u201d — grant of the MES RK 1107 \/ GF4 (2015-2017).<\/p>\n

Project manager Lee T.E. Contractual agreements within the framework of MES RK grant No. AR05131025 \u201cDirected design of preventive agents and \/ or adaptogens for plants in a series of organoelemental systems\u201d (2018-2020).<\/p>\n

Project leader Uteulin K.R. 2013-2015. \u201cObtaining highly productive forms of Taraxacum kok-saghyz Rodin\u2013 domestic producer \u043c\u0438\u043d\u0438\u0441\u0442\u0440\u043b\u0456\u0433\u0456\u043d\u0456\u04a3 \u00ab\u0422\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u044f\u043b\u0430\u0440\u0434\u044b \u043a\u043e\u043c\u043c\u0435\u0440\u0446\u0438\u0430\u043b\u0438\u0437\u0430\u0446\u0438\u044f\u043b\u0430\u0443\u00bb \u0436\u043e\u0431\u0430\u0441\u044b.of rubber\u201d, the World Bank and the Ministry of Education and Science of the Republic of Kazakhstan \u201cCommercialization of Technologies\u201d project.<\/p>\n

Project leader Uteulin K.R. Republican budget program 008 (2018-2020). «Applied scientific research in the field of space activities». Scientific and technical project «Study of the nature of plant pollution by asymmetric dimethyl hydrazine and toxic products of its transformation.» Project leader Uteulin K.R. \u00a0\u201cGrowing wild plant species in experimental conditions\u201d. Aerospace Committee of the Ministry of Defense and Aerospace Industry of the Republic of Kazakhstan.<\/p>\n

 <\/p>\n

Scientific cooperation with international and domestic organizations:<\/strong><\/p>\n

James Hutton Institute, Dundee, Scotland, UK. Dr. Jennifer Stephens, Head of Functional Genomics Dep. Field of common interest for collaboration: Plant CRISPR\/Cas9 technologies.<\/p>\n

Institute of Cytology and Genetics Novosibirsk, SD RAN, Russia. Dr, Sophia Gerasimova, leading researcher. Field of interest for collaboration: Barley CRISPR\/Cas9 genome editing.<\/p>\n

Universitat Politechnica de Valencia, Spain. Dr. Ana Fita. Head of Dep. For Crops breeding and Biotechnology. Fields of common interest for collaboration: Breeding and Biotechnology, Plant CRISPR\/Cas9 technologies.<\/p>\n

University of Illinois at Urbana-Champaign, USA. Lab. of Prof. Jack Widholm, Prof. Vera Lozovaya. Fields of common interest for collaboration: Crops biotic stress resistance, genetic engineering, metabolomics.<\/p>\n

University of Tokyo, Japan. \u041a\u043e\u043b\u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440 \u2013 Prof. Kazuko Yamaguchi-Shinozaki. \u041e\u0442\u0432\u0435\u0442\u043d\u044b\u0435 \u0440\u0435\u0430\u043a\u0446\u0438\u0438 \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u0439 \u043d\u0430 \u0430\u0431\u0438\u043e\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0441\u0442\u0440\u0435\u0441\u0441\u044b. \u0421\u0438\u0433\u043d\u0430\u043b\u044c\u043d\u0430\u044f \u0442\u0440\u0430\u043d\u0441\u0434\u0443\u043a\u0446\u0438\u044f \u0410\u0411\u041a.<\/p>\n

Tun Abdul Razak Research Centre (http:\/\/www.tarrc.co.uk\/<\/a>)\u00a0 \u2014 British Center for the Study of Natural Rubber.<\/p>\n

Russia, Novosibirsk Institute of Cytology and Genetics of the Russian Academy of Sciences.<\/p>\n

\u00a0<\/strong>Research Center «Garysh-Ecology».<\/p>\n

Aerospace Committee of the Ministry of Defense Industry of the Republic of Kazakhstan.<\/p>\n

\u00a0<\/strong><\/p>\n

Scientific and pedagogical activity (teaching, personnel training — topics of master’s, doctoral, etc.)<\/strong><\/p>\n

PhD doctoral student Gabit Bari (2019-2021), supervisor Uteulin K.R.\u00abObtaining highly productive kok-saghyz\u00a0 (Taraxacum kok-saghyz<\/em> L.) forms based on variability of morpho-physiological features\u00bb.<\/p>\n

PhD doctoral student . Erezhetova Ulzhan (2019-2021). supervisor Terletskaya N. \u201cThe effect of drought on the anatomical, morphological and photosynthetic parameters of various species and interspecific wheat hybrids in the agrocenosis\u201d.<\/p>\n

2 master’s theses were defended: Kuly Z.T., Maulenbay A.D. KazNU, Master of Technical Sciences, KazNU, 6M070100 — Biotechnology. June 2018. Supervisor Kershanskaya O.I.<\/p>\n

Defence of the Bachelor’s of Sciences Diploma, KazNAU: Sadullaeva Z.N. 2019. Thesis Manager Candidate of Agricultural Sciences Yesenbayeva G.L.<\/p>\n

 <\/p>\n

Foreign internships, honorary academic titles, awards and scholarships<\/strong><\/p>\n

Kershanskaya O.I.:<\/p>\n

Real Member \u2013 Academician of Petri Prima Academy of Science and Arts (PANA), Russia, ID RAN 1227, from 22 June 2006.<\/p>\n

Member of EBTNA (European Biotechnology Thematic Network Association).<\/p>\n

Member of SPR (Russian Society of Plant Physiologists).<\/p>\n

Fulbright Foreign Visitor CIES, USDS, University of Illinois at Urbana-Champaign, Illinois, USA. Senior Researcher. \u201cSoybean stress resistance improvement via genetic engineering of phenylpropanoid cycle\u201d. 2013-2015.<\/p>\n

Fulbright Certificate of Completion. Chairman, J. William Fulbright Foreign Scholarship Board, Assistant Secretary of State for Educational and Cultural Affairs, Washington DC, USA.<\/p>\n

Terletskaya N.V.:<\/p>\n

received in 2018 the title of associate professor.<\/p>\n

 <\/p>\n

Main publications <\/strong><\/p>\n

(the most significant for all time and for the last 5 years)<\/strong><\/p>\n

Aizhan\u00a0 Rakhmetullina, Piotr\u00a0 Zielenkiewicz, \u00a0Anna Pyrkova,\u00a0Kairat Uteulin<\/b>, Anatoliy Ivashchenko.\u00a0 Prediction of characteristics of interactions of miRNA with mRNA of GRAS, ERF, C2H2 genes of\u00a0 A. thaliana, O. sativa\u00a0 and\u00a0 Z. mays.\u00a0<\/span>Current Plant Biology\u00a0 28 (2021) 100224.\u00a0<\/span>https:\/\/doi.org\/10.1016\/j.cpb.2021.100224<\/span><\/a>\u00a0Contents lists available at ScienceDirect.\u00a0<\/span>journal homepage:\u00a0<\/span>www.elsevier.com\/locate\/cpb<\/a>\u00a0<\/span>Received 29 July 2021; Received in revised form 6 October 2021; Accepted 6 October 2021\u00a0<\/span>Available online 16 October 2021\u00a0<\/span>2214-6628\/\u00a9 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license<\/span><\/span><\/p>\n

Bari Gabit, Gainullina Karina, Gumerova Gulnar,\u00a0Uteulin Kairat,<\/u><\/b>\u00a0Golovanov Yaroslav , Chemeris Aleksey, Kuluev Bulat.\u00a0\u00abMultilocus DNA polymorphism of some rubber-bearing dandelions of Russia and Kazakhstan.\u00bb, Genetic Resources and Crop Evolution.\u00a0H \u2014 index 66.\u00a0ISSN 09259864, 15735109. Q 2. SJR 2020 0.48.\u00a0Published online 19 June 2021.<\/span><\/p>\n

 <\/p>\n

\u0410.Yu. Amerik, *, Yu. Ts. Martirosyan, , L. Yu. Martirosyan, V. M. Goldberg,\u00a0K. R. Uteulin,<\/u><\/b>\u00a0and S. D. Varfolomeev<\/span>\u0430.\u00a0Molecular Genetic Analysis of Natural Rubber Biosynthesis.\u00a0ISSN 1021-4437, Russian Journal of Plant Physiology, 2021, Vol. 68, No. 1, pp. 31\u201345.\u00a0<\/span>\u0423\u0414\u041a\u00a0581.1 DOI: 10.31857\/S0015330321010036.\u00a0Database Scopus Q2 CJR 0,38 H Indeks 41 CiteScore 1,8 ISSN 16083407, 10214437.<\/span><\/p>\n

 <\/p>\n

Kairat R. Uteulin.<\/span><\/u><\/b>\u00a0Reintroduction of Kok-saghyz (Taraxacum Kok-saghyz<\/i>\u00a0L. Rodin).\u00a0REVISTA GEINTEC-GESTAO INOVACAO E TECNOLOGIAS (Management, Innovation and Technologies).\u00a0ISSN: 2237-0722. Vol. 11 No. 2 (2021). P. 240-249.<\/span><\/p>\n

https:\/\/www.revistageintec.net\/index.php\/revista\/article\/view\/1657<\/span><\/a><\/p>\n

DOI:\u00a0<\/span>https:\/\/doi.org\/10.47059\/revistageintec.v11i2.1657<\/span><\/a><\/p>\n

Web of Science Core Collection.<\/span><\/p>\n

 <\/p>\n

K.R. Uteulin<\/span><\/u><\/b>.\u00a0Clone Selection of Kok-Saghyz (Taraxacum kok-saghyz<\/i>), A Source of Natural Rubber.\u00a0Annals of the Romanian Society for Cell Biology.\u00a0ISSN:1583-6258, Vol. 25, Issue 3,\u00a02021<\/b>, Pages.\u00a0509 \u2013 515.\u00a0Scopus.<\/span>\u00a0http:\/\/annalsofrscb.ro\/index.php<\/span>\/<\/span>journal<\/span>\/<\/span>article<\/span>\/<\/span>view<\/span>\/1525<\/span><\/a><\/p>\n

Uteulin \u041a.,<\/span><\/u><\/b>\u00a0Rakhimbayev I., Zhambakin K., Mukhambetzhanov S.,\u00a0<\/span>Bari G., Zheksenbai A., Esbolaeva B., Iskakova A., Zhabykbaev G., Akhmetzhanov M.. Technology of Kok-Saghyz (Taraxacum Kok-Saghyz<\/i>\u00a0) Reproduction in Kazakhstan.\u00a0Novel Methods and Results of Landscape Research in Europe, Central Asia and Siberia (in five volumes).\u00a0Vol. 4. Optimising Agricultural Landscapes \/main editors Viktor G. Sychev, Lothar Mueller.\u00a0\u2013 \u041c.: Publishing House FSBSI \u00abPryanishnikov Institute of Agrochemistry\u00bb,\u00a02018.<\/b>\u00a0\u2013 399 p.\u00a0Chapter IV\/18: P. 93-96.\u00a0DOI 10.25680\/8238.2018.31.76.283 ISBN 978-5-9238-0250-4 Springer Database.783391<\/span><\/p>\n

 <\/p>\n

K.R. Uteulin,<\/span><\/b>\u00a0K.Z.Zambakin.\u00a0On the need to develop technologies for producing bioplastics in Kazakhstan.\u00a0Reports of the National Academy of sciences of the Republic of Kazakhstan.\u00a0<\/span>ISSN 2224-5227 DOI: 10.32014\/2020.2518-1483.117 Volume 5, Number 333 (2020), 42 \u2013 48<\/span><\/p>\n

 <\/p>\n

Alma Ormanbekovna Bimaganbetova,\u00a0Kairat Rizabekovich Uteulin,<\/u><\/b>\u00a0Anuar Bulatovich Atygaev, Olga Alekseevna Fedorina, Yelena Yurievna Stepanova, Yerlan Achmedovich Bekeshev.\u00a0Ecological Modelling Research of Transformations of Unsymmetrical Dimethylhydrazine and N-Nitrodimethylamine.\u00a0Systematic Reviews in Pharmacy SRP.\u00a02020;\u00a0<\/b>11(6): 179-181.\u00a0<\/span>\u041f\u043e\u0440\u044f\u0434\u043a\u043e\u0432\u044b\u0439\u00a0\u043d\u043e\u043c\u0435\u0440\u00a027.\u00a0Correspondence: Uteulin K.R. , doi:10.31838\/srp.2020.6.28 H Indeks 14.<\/span><\/p>\n

ORCID iD\u00a0<\/span>https:\/\/orcid.org\/0000-0002-<\/span><\/a><\/p>\n

Database Scopus (<\/span>http:\/\/www.scimagojr.com<\/span><\/a>)\u00a0<\/span>http:\/\/www.sysrevpharm.org\/<\/span><\/a><\/p>\n

ISSN \u2014 09758453, 09762779<\/span><\/p>\n

Q2 second quartile, percentiles citeScore 68 inclusive [CiteScore and citeScore percentiles].<\/span><\/p>\n

Total Cites Systematic Reviews in Pharmacy 165 in 2019.<\/span><\/p>\n

 <\/p>\n

\u00a0<\/em><\/strong>Kershanskaya O.I. New breakthrough CRISPR\/Cas9 biotechnology of genome editing for creation of elite barley cultivars in Kazakhstan. European Biotechnology Congress, Valencia, Spain, April 11-13, 2019. Oral Presentation. Chair of Session.<\/p>\n

Kershanskaya O.I., Nelidova D.S., Esenbaeva G.L., Mukiyanova G.S., Karabekova A.N., Nelidov S.N. Genome Editing CRISPR\/Cas9 Biotechnology is a New Great Opportunity for Elite Crops Creation. The Eurobiotech Journal. 2019. N2. In press.<\/p>\n

Kershanskaya OI, Mukiyanova GS, Nelidova DS, Esenbayeva GL, Nelidov SN, Uteulin KR, Stephens J. CRISPR \/ Cas9 editing the genome of agricultural cultures in development biology and agriculture. Materials of the XI Congress OFR, Kazan, 2019. In print<\/p>\n

Kershanskaya O.I., Kuli Zh., Maulenbay A., Nelidova D., Nelidov S.N., Stephens J. New CRISPR\/Cas9 gene editing technology for development of Agricultural Biotechnology. Proceedings of the All-Russian International Scientific Conference, Irkutsk. 2018. P. 1434-1437.<\/p>\n

Kershanskaya O.I., Kuli Zh., Maulenbay A., Nelidova D., Uteulin K.R., Nelidov S.N., Stephens J. Establishment of new gene editing CRISPR\/Cas9 technology for creation of elite barley cultivars in Kazakhstan and UK. Genes and Cells. 2018. N 2. P. 35-36.<\/p>\n

Kershanskaya O.I. New breakthrough CRISPR\/Cas9 biotechnology of genome editing for creation of elite crops in Kazakhstan. Review. Proceedings of the National Academy of Science of RK, 2018. N 5. P. 24-40.<\/p>\n

Kershanskaya O.I., Kuli Zh., Maulenbay A., Esenbaeva G.L., Nelidova D., Nelidov S.N., Stephens J. CRISPR\/Cas9 biotechnology for creation of elite diseases resistant barley cultivars in Kazakhstan and UK. Proceedings of International Symposium Astana Biotech 2018. Astana, 2018. P. 93.<\/p>\n

\u041a\u0435\u0440\u0448\u0430\u043d\u0441\u043a\u0430\u044f O.\u0418., \u041d\u0435\u043b\u0438\u0434\u043e\u0432\u0430 \u0414.\u0421., \u041b\u043e\u0437\u043e\u0432\u0430\u044f \u0412.\u0412., \u0417\u0435\u0440\u043d\u043e\u0432\u0430 \u041e.\u0412., \u041b\u044b\u0433\u0438\u043d \u0410.\u0412., \u0412\u0438\u0434\u0445\u043e\u043b\u043c \u0414\u0436.\u041c. \u041f\u0435\u0440\u0441\u043f\u0435\u043a\u0442\u0438\u0432\u044b \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f \u2026\u043e\u043c\u0438\u043a\u0441 \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0439 \u043a\u0430\u043a \u043d\u043e\u0432\u043e\u0433\u043e \u044d\u0442\u0430\u043f\u0430 \u0431\u0438\u043e\u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0438 \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u0439 \u0432 \u043f\u043e\u0441\u0442-\u0433\u0435\u043d\u043e\u043c\u043d\u0443\u044e \u044d\u0440\u0443. \u0421\u0431\u043e\u0440\u043d\u0438\u043a \u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u043e\u0432 \u0434\u043e\u043a\u043b\u0430\u0434\u043e\u0432. \u0413\u043e\u0434\u0438\u0447\u043d\u043e\u0435 \u0441\u043e\u0431\u0440\u0430\u043d\u0438\u0435 \u041e\u0431\u0449\u0435\u0441\u0442\u0432\u0430 \u0444\u0438\u0437\u0438\u043e\u043b\u043e\u0433\u043e\u0432 \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u0439 \u0420\u043e\u0441\u0441\u0438\u0438. \u042d\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u0430\u044f \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u0439: \u0444\u0443\u043d\u0434\u0430\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u044b\u0435 \u0438 \u043f\u0440\u0438\u043a\u043b\u0430\u0434\u043d\u044b\u0435 \u0430\u0441\u043f\u0435\u043a\u0442\u044b. 18-24 \u0441\u0435\u043d\u0442\u044f\u0431\u0440\u044f 2017 \u0433\u043e\u0434\u0430, \u041a\u0440\u044b\u043c, \u0421\u0443\u0434\u0430\u043a. \u0421. 189.<\/p>\n

Kershanskaya O., Stephens J. Establishment and evaluation of new gene editing and germ-line transformation agricultural technologies for creation of new elite disease resistant barley cultivars in the UK and Kazakhstan. \u0421\u0431\u043e\u0440\u043d\u0438\u043a \u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u043e\u0432 \u0434\u043e\u043a\u043b\u0430\u0434\u043e\u0432. \u0413\u043e\u0434\u0438\u0447\u043d\u043e\u0435 \u0441\u043e\u0431\u0440\u0430\u043d\u0438\u0435 \u041e\u0431\u0449\u0435\u0441\u0442\u0432\u0430 \u0444\u0438\u0437\u0438\u043e\u043b\u043e\u0433\u043e\u0432 \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u0439 \u0420\u043e\u0441\u0441\u0438\u0438. \u042d\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u0430\u044f \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u0439: \u0444\u0443\u043d\u0434\u0430\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u044b\u0435 \u0438 \u043f\u0440\u0438\u043a\u043b\u0430\u0434\u043d\u044b\u0435 \u0430\u0441\u043f\u0435\u043a\u0442\u044b. 18-24 \u0441\u0435\u043d\u0442\u044f\u0431\u0440\u044f 2017 \u0433\u043e\u0434\u0430, \u041a\u0440\u044b\u043c, \u0421\u0443\u0434\u0430\u043a. \u0421. 190.<\/p>\n

\u041a\u0435\u0440\u0448\u0430\u043d\u0441\u043a\u0430\u044f \u041e.\u0418., \u0410\u0431\u0434\u0443\u043b\u0436\u0430\u043d\u043e\u0432\u0430 \u041c.\u0410., \u0415\u0441\u0435\u043d\u0431\u0430\u0435\u0432\u0430 \u0413.\u041b., \u041d\u0435\u043b\u0438\u0434\u043e\u0432\u0430 \u0414.\u0421., \u0418\u0441\u043c\u0430\u0438\u043b\u043e\u0432\u0430 \u041c.\u041c., \u0414\u0430\u0443\u043b\u0435\u0442\u0431\u0430\u0435\u0432\u0430 \u0421.\u041a., \u0418\u0441\u0430\u0431\u0435\u043a\u043e\u0432\u0430 \u0410.\u0428. \u041f\u0435\u0440\u0441\u043f\u0435\u043a\u0442\u0438\u0432\u044b \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f \u2026\u043e\u043c\u0438\u043a\u0441 \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0439 \u043a\u0430\u043a \u043d\u043e\u0432\u044b\u0439 \u044d\u0442\u0430\u043f \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f \u0431\u0438\u043e\u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0438 \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u0439 \u0432 \u043f\u043e\u0441\u0442-\u0433\u0435\u043d\u043e\u043c\u043d\u043e\u0439 \u044d\u0440\u0435 VI \u0412\u0441\u0435\u0440\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u0438\u0439 \u0441\u0438\u043c\u043f\u043e\u0437\u0438\u0443\u043c \u00ab\u0422\u0440\u0430\u043d\u0441\u0433\u0435\u043d\u043d\u044b\u0435 \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u044f: \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0438 \u0441\u043e\u0437\u0434\u0430\u043d\u0438\u044f, \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0441\u0432\u043e\u0439\u0441\u0442\u0432\u0430, \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435, \u0431\u0438\u043e\u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u044c\u00bb \u041c\u043e\u0441\u043a\u0432\u0430, 16-21 \u043d\u043e\u044f\u0431\u0440\u044f 2016. \u0421. 73-76.<\/p>\n

Kershanskaya O.I., Zernova O.V., Abdulzhanova M.A., Nelidova D.S., Lozovaya V.V. Improvement of soybean innate resistance to stress through enhancing lignification by genetic engineering. VI \u0412\u0441\u0435\u0440\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u0438\u0439 \u0441\u0438\u043c\u043f\u043e\u0437\u0438\u0443\u043c \u0438 \u0441\u0431\u043e\u0440\u043d\u0438\u043a \u00ab\u0422\u0440\u0430\u043d\u0441\u0433\u0435\u043d\u043d\u044b\u0435 \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u044f: \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0438 \u0441\u043e\u0437\u0434\u0430\u043d\u0438\u044f, \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0441\u0432\u043e\u0439\u0441\u0442\u0432\u0430, \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435, \u0431\u0438\u043e\u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u044c\u00bb \u041c\u043e\u0441\u043a\u0432\u0430, 16-21 \u043d\u043e\u044f. 2016. \u0421. 77-80.<\/p>\n

Kershanskaya \u041e.I. Perspective of \u2026omics research development in Kazakhstan as a new step of plant biotechnology in post-genomics era. Proceedings of the National Academy of Sciences of the Republic of Kazakhstan. 2015. N 3. P. 158-178.<\/p>\n

Kershanskaya \u041e.I., Abdulzhanova \u041c.\u0410., Ismailova \u041c.\u041c., Dauletbaeva S. K., Gulevich \u0410. \u0410. Anti-oxidative stress fe-sod <\/em>gene cloning for soybean genetic transformation. The National Academy of Sciences of the Republic of Kazakhstan Series of Biological And Medical. ISSN 2224-5308. 2015. Vol. 1, 307, 99 \u2013 109.<\/p>\n

Kershanskaya \u041e.I., Abdulzhanova \u041c.\u0410., Esenbaeva G.L., Nelidova D.S., Zernova O.V., Lozovaya V.V., Widholm J.M. Improvement of inner soybean diseases resistance by genetic engineering of phenylpropanoid cycle: molecular detection of transgenic plants. Biotechnology. Theory and practice. 2015. N 1. P. 35-47.<\/p>\n

Kershanskaya O. I., Esenbaeva\u00a0 G.L., Nelidova D.S., Ismailova M.M., Dauletbaeva S.K., Abdulzhanova M. A., Isabekova\u00a0 A.Sh. Germ-line genetic transformation technique improve soybean innate resistance to stress through enhancing lignification. Transgenic Research, Springer. 2015.<\/p>\n

Kershanskaya O.I. Perspective of \u2026omics research development as a new step of plant biotechnology in post- genomics era. 8th Euro Biotechnology Congress August 18-20, 2015. Frankfurt, Germany.<\/p>\n

Kershanskaya O.I. A new step of plant\u00a0 biotechnology in post- genomics era via genetic engineering of the key metabolic pathways. The World Congress of Agriculture — 2015. More Advanced, More Healthy, and More Safety. 13-15, Nov. 2015. Qingdao, China.<\/p>\n

Kershanskaya O.I. A new step of plant biotechnology in post- genomics era via genetic engineering of the key metabolic pathways. 3rd<\/sup> conference of cereal biotechnology, November 2-4, 2015. Berlin, Germany.<\/p>\n

Kershanskaya O.I., Abdulzhanova M.A., Lozovaya V.V., Widholm J.M. Soybean genomics improving for innate resistance to biotic stresses via genetic engineering of the phenylpropanoid pathway. Crops 2015. Improving Agriculture through Genomics. May 18-21, 2015. Huntsville, Alabama, USA.<\/p>\n

Kershanskaya \u041e., Nelidova D. Wheat crop improvement via genetic modification of photosynthesis. International wheat congress 2015. 20-25 September, 2015. Sydney, Australia.<\/p>\n

Kershanskaya O.I., Abdulzhanova \u041c.\u0410., Esenbaeva G.L., Nelidova D.S., Zernova O.V., Lozovaya V.V., Widholm J.M. Genetic engineering of phenylpropanoid cycle for improvement of inner soybean diseases resistance. VIII Congress of All-Russia Society of Plant Physiologists \u00abPlants in conditions of the global and local natural-climatic and anthropogenic treatments\u00bb, 21-26 Sept. 2015. Petrozavodsk, Karelia, Russia.<\/p>\n

Kershanskaya O.I. A new step of plant biotechnology in post- genomics era. II International Scientific Conference \u00abGenetics and biotechnology of XXI century: problems, achievements, perspectives\u00bb, 13-16 Oct. 2015. Minsk, Belarussia.<\/p>\n

Kershanskaya O.I. Perspective of \u2026omics research development as a new step of plant biotechnology in post- genomics era. II International Scientific Conference \u00abGenetics and biotechnology of XXI century: problems, achievements, perspectives\u00bb, 13-16 October 2015. Minsk, Belarussia.<\/p>\n

Terletskaya N., Zorbekova A., Altayeva N., Bari G., Erezhetova U. Effect of drought for growth parameters and pigment complex of wheat lines obtained from interspecific crosses. Experimental Biology. \u21163 (76). 2018. \u0420.130-139.<\/p>\n

Terletskaya N., Zobova N., Stupko V., Shuyskaya E. Growth and photosynthetic reactions of different species of wheat seedlings under drought and salt stress \/\/ Periodicum Biologorum\u00a0\u2013 2017 \u2212 V. 119, \u21161. \u2212 37\u201345. DOI: 10.18054\/pb.v119i1.4408<\/p>\n

Terletskaya N.V., Kurmanbayeva M.S.\u00a0Change of leaf anatomical parameters of different species of wheat seedlings under conditions of drought and salt stress\u00a0\/\/ Pak. J. Bot.\u00a0\u2013 2017. \u221249 (3)\u00a0\u2013\u0420. 857-865.<\/p>\n

Terletskaya N.V. et al. Study of the resistance of the photosynthetic apparatus of soft wheat (T.<\/em> aestivum<\/em> L.) and its wild relatives to abiotic stressors in vivo and in vitro: Monograph. — Almaty, 2017.-172 p.<\/p>\n

Khailenko N.A., Altayeva N.A., Iskakova A.B. Morphophysiological cytogenetic features of interspecific wheat hybrids: Monograph. Almaty, 2017. 232<\/p>\n

Lee T.E. et al. Polyunsaturated Fatty Acids Content in Soybean Oil. \/\/ Advance Journal of Food Science and Technology. 2016.N.12(10).\u00a0 P.568-573.<\/p>\n

Lee T.E. et al. Anatomical peculiarities in wheat (Triticum Aestivum L<\/em>.) varieties under copper stress. \/\/ Pak. J. Bot<\/em>., 2016. 48(4): 1399-1405 (IF: 0.658).<\/p>\n

Lee T.E.\u00a0 et al. Amino Acid Profiles and Sucrose Content in Developing Soybean Seeds. European Biotechnology Conress. 05-07 May 2016, (\u0420\u0438\u0433\u0430, \u041b\u0430\u0442\u0432\u0438\u044f) \/\/ Journal of Biotechnology\u00a0\u00a0\u00a0\u0422\u043e\u043c:\u00a0231. \u2013P.:\u00a0S41-42.<\/p>\n

Lee T.E.\u00a0 et al. Amino Acids Profiling in Developing Seeds. European Biotechnology Congress.25-27 May 2017, (Dubrovnik, Croatia).<\/p>\n

Uteulin K.R., Baytulin I.O. About the need for recovery degraded populations of kok-saghyz. Reports of the National Academy of Sciences of the Republic of Kazakhstan. 2017. \u21162. C.56-61.<\/p>\n

Uteulin K.R, Bari G.T., Rakhimbaev I.R. Pelleted seeds Dandelion kok-saghyz (Tarxacum kok-saghyz<\/em> Rodin) \u2013 producer of natural plant rubber. Solving problem of small-seeded kok-saghyz. Report of\u00a0 National Academy of Sciences of the Republic of Kazakhstan., 2016,V.2, N 306, — P.123-127.<\/p>\n

Agapov O.A., Fedorina O.A., Atygaev A.B., Uteulin K.R., Zheksenbai A., Kazkeev D., Aldasugurova Ch.Zh., Kurbatova N.V. Influence of unsymmetrical hydrazine on seed germination, growth and on anatomical parameter seedlings of wild plant species. Scientific and technical journal «Science News of Kazakhstan». Almaty 2019. \u2116 1 (139). P.210-22.<\/p>\n

 <\/p>\n

Patents:<\/strong><\/p>\n

Kershanskaya O.I. The Patent application was accepted and the formal examination of the patent for the invention \u201cNew method of genetic transformation of barley\u201d 2019.0184.1 from 11.03.2019 was successfully completed. Authors: Kershanskaya OI, Esenbaeva G.L., Mukiyanova G.S., Nelidova DS, Sadullaeva Z.N.<\/strong><\/p>\n

Lee T.E. et al. A method for identifying high-protein leguminous crops. The number of the utility model is 30716. Published 12\/25\/2015<\/p>\n

Terletskaya N.V., Altaeva N.A., Zorbekova A.N. A way to create alloplasmatic drought-resistant wheat line. Utility model number: 107266. Published 12\/21\/2018<\/p>\n

Terletskaya N.V. et al. A method for producing photosynthetic callus wheat culture. Utility model number: 1642. Published: 09\/15\/2016<\/p>\n

Altaeva N.A., Khaylenko N.A. The method for determining hybrid wheat plants in interspecific crosses with the species T.kiharae. The number of the utility model: 1751. Posted 09\/26\/2016<\/p>\n

Uteulin KR, et al. The method of obtaining the original seeds \u201cTKS-1 \u2033 — prototype varieties of kok-sagyz (Taraxacum kok-saghyz<\/em>). Innovation patent number: 31285. Published: 06\/30\/2016.<\/p>\n

Uteulin K.R., Zhambakin K.J. et al. Certificate of the author of a selection achievement. Variety of Dandelion, kok-saghyz «Saryzhaz» No. 4395 (2018).<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

Services (which can be provided by the laboratory for commercialization, etc.):<\/strong><\/p>\n

Unique genetic constructions for genetic engineering and plant genome editing for crop improvement. Gene cloning methods.<\/p>\n

Training and teaching of modern genomics, metabolomics, genetic engineering, gene and genome editing biotechnologies in major crops.<\/p>\n

\u00a0<\/strong><\/p>\n

Image products:<\/strong><\/p>\n

Seeds and plants of high-yielding priority crops resistant to diseases caused by micropathogens and viruses penetration.<\/p>\n

Patents and biotechnologies for genetic transformation and genes\/genome editing of priority crops.<\/p>\n

 <\/p>\n

\"1\"<\/a>\"2\"<\/a>\"3\"<\/a>\"4\"<\/a>\"5\"<\/a>\"6\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Head of the laboratory Dr. Kairat Uteulin,\u00a0 Professor Fax:\u00a0 +7(727) 394 7562 Phone: 8 705 185 0224 E-mail: gen_uteulink@mail.ru Author ID\u00a0Scopus\u00a0 6602865844 Researcher ID Web of Science\u00a0L-3508-2018 ORCID ID 0000-0002-5459-0902   Laboratory staff Kershanskaya O.I. — Chief Researcher, Doctor of Biological Sciences, Professor. Terletskaya N.V. — Leading Researcher, Candidate of Biological Sciences, Associate Professor. Lee T.E. — Leading Researcher, Candidate<\/p>\n

<\/div>\n

Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-23884","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ipbb.kz\/eng\/wp-json\/wp\/v2\/pages\/23884","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ipbb.kz\/eng\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ipbb.kz\/eng\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ipbb.kz\/eng\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ipbb.kz\/eng\/wp-json\/wp\/v2\/comments?post=23884"}],"version-history":[{"count":19,"href":"https:\/\/ipbb.kz\/eng\/wp-json\/wp\/v2\/pages\/23884\/revisions"}],"predecessor-version":[{"id":24949,"href":"https:\/\/ipbb.kz\/eng\/wp-json\/wp\/v2\/pages\/23884\/revisions\/24949"}],"wp:attachment":[{"href":"https:\/\/ipbb.kz\/eng\/wp-json\/wp\/v2\/media?parent=23884"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}